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Research
Understanding how neutrophils shape inflammation, aging, host defense, and tissue repair.
From inflammation resolution to extracellular vesicles, we investigate the mechanisms that determine how neutrophils protect and repair tissues across health and disease.
Our Research Themes
Extracellular Vesicles (LAND-Vs)
We discovered Large Aging Neutrophil-Derived Vesicles (LAND-Vs) and investigate how neutrophil-derived vesicles regulate complement activation and inflammation resolution.
Inflammation Resolution
We investigate how neutrophils transition from inflammatory effector cells into pro-resolution states that restore tissue homeostasis and terminate excessive inflammation.
Immune Aging
We study how aging reshapes neutrophil development, function, and resolution programs, contributing to chronic inflammation and impaired tissue repair.
Migration & Cell Biology
We investigate the signaling and cytoskeletal mechanisms that control neutrophil migration, adhesion, polarity, and tissue recruitment.
Infection & Host Defense
Using bacterial infection and inflammatory disease models, we examine how neutrophils coordinate antimicrobial defense and immune signaling.
Membrane Biology & Cell Death
We investigate how membrane remodeling, lipid organization, and inflammatory cell death pathways regulate neutrophil function and disease outcomes.
