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LAB MISSION
Uncovering the mysteries of Neutrophil Biology
Neutrophils have long been viewed as short-lived inflammatory cells. Our work challenges this paradigm by uncovering how neutrophils actively regulate inflammation resolution, tissue repair, and immune homeostasis.
By integrating immunology, cell biology, vesicle biology, and disease models, we investigate how neutrophil functional states shape health and disease across aging and infection.
RESEARCH AREA
We investigate how neutrophils regulate inflammation, tissue damage, and immune resolution across aging and disease.
Inflammation Resolution
We study how neutrophils transition from inflammatory effector cells into pro-resolution states that restore tissue homeostasis.
Extracellular Vesicles
We investigate neutrophil-derived vesicles, including LAND-Vs, and their roles in complement regulation and inflammation resolution.
Immune Aging
Our work explores how host aging reshapes neutrophil function and contributes to chronic inflammation, impaired repair, and disease susceptibility.
Infection & Host Defense
Using infection models and inflammatory disease, we examine how neutrophils coordinate antimicrobial defense and immune signaling.
